author: creativelivenew 8 January 2010

Man's use of enzymes dates back to the earliest times of civilization. Important human activities such as the production of certain types of foods and beverages, and the tanning of hides and skins to produce leather for garments, serendipitously took advantage of enzyme activities. Important advances in our understanding of the nature of enzymes and their action were made in the late 19th and early 20th centuries, seeding the explosive expansion from the 1950s and 60s onward to the present billion dollar enzyme industry. Recent developments in the fields of genetic engineering and protein chemistry are bringing ever more powerful means of analysis to bear on the study of enzyme structure and function that will undoubtedly lead to the rational modification of enzymes to match specific requirements as well as the design of new enzymes with novel properties

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author: silanh 4 November 2009

When The Silence of the Lambs took the Academy Awards ceremony by storm in 1992, winning in five major categories (Best Picture, Best Director - Jonathan Demme, Best Actor - Anthony Hopkins, Best Actress - Jodie Foster, and Best Adapted Screenplay - Ted Tally), it beat the odds in more ways than one. Granted, 1991 was a slow year for movies, and many pundits have remarked that the Oscar field was among the weakest ever (the other contenders were Disney's Beauty and the Beast, Bugsy, JFK, and the overrated The Prince of Tides), but the strong showing of The Silence of the Lambs was a surprise to almost everyone. In the first place, it was released in February 1991, a date thought to be beyond the short memories of the Academy members. Secondly, it is a dark psychological thriller - the kind of movie that occasionally receives a Best Picture nomination, but almost never takes home the statuette.

Although The Silence of the Lambs is brilliantly constructed and powerfully acted, and became one of the most recognizable thrillers of the '90s, it was neither the best movie of the year (a citation I would award to Beauty and the Beast) nor even the best thriller (overall, Dead Again impressed me more). The Silence of the Lambs contains a number of inarguably great scenes, but the screenplay, adapted from Thomas Harris' novel, suffers from a split personality. The scenes featuring Hannibal Lecter (Anthony Hopkins) are the stuff of legends. However, the rest of the movie, which concentrates on the pursuit of serial killer Buffalo Bill (Ted Levine), has a familiar, derivative feel. In truth, the climax couldn't be more mundane.

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